PGD gender selection for non-Mendelian disorders with unequal sex incidence

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PGD gender selection for non-Mendelian disorders with unequal sex incidence.

Preimplantation genetic diagnosis (PGD) was originally developed for couples whose potential offspring were at risk of severe Mendelian disorders, but has since been extended to other indications. One possible use of PGD is to perform gender selection for couples whose offspring are at increased risk of disorders that do not follow Mendelian inheritance, but which are substantially more common ...

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Following ethical issues, many of unwanted pregnancies and abortions can be avoided. Several factors such as cultural, social, religious, and economic issues, as well as medical reasons such as the existence of some diseases related to chromosome X encourage couples to choose traditional or new treatment methods for selecting their child’s gender. The establishment of family balance is another ...

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We model parental sex selection and the equilibrium sex ratio. With intrinsic son preference, sex selection results in a male-biased sex ratio. This is ine¢ cient, due to a marriage market congestion externality. Medical innovations that facilitate selection increase ine¢ ciency. If son preference arises endogenously, due to population growth causing an excess of women on the marriage market, s...

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Sex Selection and Gender Balance

We model parental sex selection and the equilibrium sex ratio. With intrinsic son preference, sex selection results in a male-biased sex ratio. This is ine¢ cient, due to a marriage market congestion externality. Medical innovations that facilitate selection increase ine¢ ciency. If son preference arises endogenously, due to population growth causing an excess of women on the marriage market, s...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2008

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/dem433